Vacant PhD fellowship in “Epitranscriptomics and cancer”
A PhD position is available at the Department of Cellular and Molecular Medicine (ICMM) in the H. Nielsen Group headed by Professor Henrik Nielsen.
The position starts 1 January 2022 and highly motivated and committed candidates with an interest in cancer and RNA biology are encouraged to apply.
In this project, we emphasize the role of RNA-guided RNA-modifications, such as ribose methylation and pseudouridylation of ribosomal RNA and how these modification impact translation in normal cells and in cancer. The project builds on recent publications from the group demonstrating pronounced perturbations of the RNA modification pattern in cancer cell lines and patient samples as well as detailed molecular analyses of the impact of individual modifications on the translation process. The specific aim is to establish the connection between expression of guide RNAs, the instalment of nucleotide modifications and the consequences at the level of mRNA recruitment and translation for selected sites of particular relevance in cancer. The project is a collaborative effort with clinical research groups to ensure its relevance to clinical practise.
Application deadline: 15 October 2021, 23.59 p.m. CET.
Read more about the vacant PhD fellowship in “Epitranscriptomics and cancer”