Tommy J
Postdoc
Glycomics Program
Blegdamsvej 3
2200 København N.
The overarching goals for Clausen Group and Copenhagen Center for Glycomics (CCG) are to identify diseases caused by defects in glycosylation and to uncover novel functions of glycosylation.
Technical barriers have left the glycomics field under-explored with a huge potential for discovery and biomedical applications. In Clausen group we are developing novel enabling technologies to overcome these barriers using a genetic approach to glycomics. Our unique strategies to glycomics are based on a genetic entry point and designed for open-ended and opportunistic Ome-wide discovery. The grand idea is to transform glycosciences from a field largely only approachable to specialists into a mainstream “Omics” field approachable to non-specialists with an ease comparable to the genome and proteome fields today. Our specific discovery programs GlycoDisplay, GlycoCRISPR, GlycoDesign, and GlycoView are developing unique reagents, tools and community resources that will help bring glycosciences into a new phase where studying the biology of glycans becomes as intuitive as building with “Lego”.
In 2024, Thapakorn’s work on cancer-specific antibody discovery was partially supported by the NEYE Foundation (https://www.neye.dk/blog/neye-fonden/)
ID: 283284830
Flest downloads
-
19
downloads
Direct observation of glycans bonded to proteins and lipids at the single-molecule level
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet