GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

The GlycoDomainViewer is a bioinformatic tool to aid in the mining of glycoproteomic data sets from different sources and facilitate incorporation of glycosylation into studies of protein structure and function. We present a version 2.0 of GlycoDomainViewer incorporating a number of advanced features, which enhances visibility and accessibility of the wealth of glycoproteomic data being generated. The GlycoDomainViewer enables visual exploration of glycoproteomic data, incorporating information from recent N- and O-glycoproteome studies on human and animal cell lines and some organs and body fluids. The initial data comprises sites of glycosylation for N-linked, O-GalNAc, O-Fucose, O-Xyl, O-Mannose (in both human and yeast) and cytosolic O-GlcNAc type. The data made available via this tool will be regularly updated to improve the coverage of known glycosylation sites and data sets, reflecting the advances currently being made in characterisation of glycoproteomes. The tool is available at https://glycodomain.glycomics.ku.dk.

OriginalsprogEngelsk
TidsskriftGlycobiology
Vol/bind28
Udgave nummer3
Sider (fra-til)131-136
Antal sider6
ISSN0959-6658
DOI
StatusUdgivet - 1 mar. 2018

ID: 188399203