The cell is the basis of all life and disease. Therefore understanding the molecular functions of eukaryotic cells and their communication with other cells and the environment is at the heart of understanding healthy life as well as disease at the molecular level. The focus of the department is the functional cell, its genetic components and molecular cellular mechanisms in a medical context. With a firm foundation in the basic function of the normal and differentiating cell an understanding of the molecular, cellular and genetic mechanisms behind disease and aging is sought. The aim of the department is to exploit new discoveries and mechanistic insight as guidelines for translational medicine in terms of novel principles for treatment and diagnosis of disease in an internationally competitive, inspiring, productive scientific environment exploiting state of the art (and beyond) methodology.
Our cellular and genetic understanding of disease at the molecular and cell communication level is presently expanding at unprecedented pace. This is especially true for the role of genetic components, but intra and inter cellular molecular communication networks are also being rapidly unravelled. As in most other areas of science, technology innovation and development set limitations and present new opportunities for experimental approaches. The recent developments within genomic deep sequencing illustrate such a "quantum jump" most dramatically. Thus technical progress paves the road to the future allowing new scientific questions to be asked and answered. Consequently, the Department of Cellular and Molecular Medicine strives to implement state of the art technology for molecular cellular studies and also contributes the development of new, cutting-edge techniques.
The research programmes at the department comprehensively cover molecular mechanistic aspects of cellular function in a medical context including: Morphogenesis and differentiation, glycomics, medical genetics, RNA and gene medicine, and molecular aging.