Tritsaris Group

The group is teaching medical, odontology and molecular biomedicine undergraduate students in cell biology. In addition, we supervise molecular biomedicine bachelor and master students. Katerina Tritsaris is Deputy head of department for Education and course leader of the course “Medical cell and tissue biology. 

• Pulsed electric fields stimulate microglial transmitter release of VEGF, IL-8 and GLP-1 and activate endothelial cells through paracrine signaling Hyldahl F, Hem-Jensen E, Rahbek UL, Tritsaris K, Dissing, S. Neurochem. Int., 2023.
• Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure Oernbo EK, Steffensen AB, Razzaghi Khamesi P, Toft-Bertelsen TL, Barbuskaite D, Vilhardt F, Gerkau NJ, Tritsaris K, Simonsen AH, Lolansen SD, Andreassen SN, Hasselbalch SG, Zeuthen T, Rose CR, Kurtcuoglu, Fluids barriers CNS, 2022.
• Evaluating the involvement of cerebral microvascular endothelial Na+/K+-ATPase and Na+-K+-2Cl- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration Lykke K, Assentoft M, Hørlyck S, Helms HC, Stoica A, Toft-Bertelsen TL, Tritsaris K, Vilhardt F, Brodin B, MacAulay N. J Cereb blood flow metab, 2019.
• Rectal Insulin Instillation Inhibits Inflammation and Tumor Development in Chemically Induced Colitis Yassin M, Sadowska Z, Tritsaris K, Kissow H, Hansen CHF, Forman JL, Rogler G, Troelsen JT, Pedersen AE, Olsen J. J Chrohns colitis, 2018.

• Pulsed electric fields stimulate microglial transmitter release of VEGF, IL-8 and GLP-1 and activate endothelial cells through paracrine signaling Hyldahl F, Hem-Jensen E, Rahbek UL, Tritsaris K, Dissing, S. Neurochem. Int., 2023.
• Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure Oernbo EK, Steffensen AB, Razzaghi Khamesi P, Toft-Bertelsen TL, Barbuskaite D, Vilhardt F, Gerkau NJ, Tritsaris K, Simonsen AH, Lolansen SD, Andreassen SN, Hasselbalch SG, Zeuthen T, Rose CR, Kurtcuoglu, Fluids barriers CNS, 2022.
• Evaluating the involvement of cerebral microvascular endothelial Na+/K+-ATPase and Na+-K+-2Cl- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration Lykke K, Assentoft M, Hørlyck S, Helms HC, Stoica A, Toft-Bertelsen TL, Tritsaris K, Vilhardt F, Brodin B, MacAulay N. J Cereb blood flow metab, 2019.
• Rectal Insulin Instillation Inhibits Inflammation and Tumor Development in Chemically Induced Colitis Yassin M, Sadowska Z, Tritsaris K, Kissow H, Hansen CHF, Forman JL, Rogler G, Troelsen JT, Pedersen AE, Olsen J. J Chrohns colitis, 2018.

• Egholm C, Khammy MM, Dalsgaard T, Mazur A, Tritsaris K, Hansen AJ, Aalkjaer C, Dissing S. GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries.  Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1214-H1224.
   
• Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, Yang X, Nakamura M, Wang J, Zhuang R, Morikawa H, Xue Y, Braun H, Beyaert R, Samani N, Nakae S, Hams E, Dissing S, Fallon PG, Langer R, Cao Y. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages.  Nat Commun. 2016,  7:11385-11403.
  
  
• Bosteen MH, Tritsaris K, Hansen AJ, Dissing S. IL-17A potentiates TNFα-induced secretion from human endothelial cells and alters barrier functions controlling neutrophils rights of passage. Pflugers Arch. 2014 466(5):961-72.
  
  
• Nielsen SR, Hammer T, Gibson J, Pepper MS, Nisato RE, Dissing S, Tritsaris K. IL-27 inhibits lymphatic endothelial cell proliferation by STAT1-regulated gene expression. Microcirculation. 2013 Aug;20(6):555-64.
  
  
• Cao R, Xue Y, Hedlund EM, Zhong Z, Tritsaris K, Tondelli B, Lucchini F, Zhu Z, Dissing S, Cao Y. VEGFR1-mediated pericyte ablation links VEGF and PlGF to cancer-associated retinopathy.  Proc Natl Acad Sci USA. 2010 Jan 12;107(2):856-61.
  
  
• Hammer T, Tritsaris K, Hübschmann MV, Gibson J, Nisato RE, Pepper MS, Dissing S. IL-20 activates human lymphatic endothelial cells causing cell signalling and tube formation.  Microvasc Res. 2009 Jun;78(1):25-32.
  
  
• Tritsaris K, Myren M, Ditlev SB, Hübschmann MV, van der Blom I, Hansen AJ, Olsen UB, Cao R, Zhang J, Jia T, Wahlberg E, Dissing S, Cao Y. IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs.  Proc Natl Acad Sci USA. 2007 104(39):15364-9.
  
  
• Thamsborg G, Florescu A, Oturai P, Fallentin E, Tritsaris K, Dissing S. Treatment of knee osteoarthritis with pulsed electromagnetic fields: a randomized, double-blind, placebo-controlled study.  Osteoarthritis Cartilage. 2005 Jul;13(7):575-81.
  
  
• Rahbek UL, Dissing S, Thomassen C, Hansen AJ, Tritsaris K. Nerve growth factor activates aorta endothelial cells causing PI3K/Akt- and ERK-dependent migration.  Pflugers Arch. 2005 450(5):355-61.
  
  
• Cao R, Björndahl MA, Religa P, Clasper S, Garvin S, Galter D, Meister B, Ikomi F, Tritsaris K, Dissing S, Ohhashi T, Jackson DG, Cao Y. PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis.  Cancer Cell. 2004 6(4):333-45